Disfunção
Tratamento da disfunção erétil
O tratamento depende da causa. Suplementação de testosterona pode ser usada para casos de deficiência hormonal. Porém, geralmente a causa é falta de suprimento adequado de sangue para o pênis como resultado de danos às paredes internas dos vasos sanguíneos. Há algum tempo atrás, substâncias médicas (ex: apomorfina) eram injetadas diretamente no tecido erétil do corpo do pênis para tratar a impotência. Em alguns casos onde não houve resposta ao tratamento médico, poderia ser aconselhado um implante peniano (prótese peniana). Depois da descoberta de agentes orais que dilatam os vasos sanguíneos do corpo cavernoso, começou-se a usar métodos mais conservadores.
Inibidores de PDE5
Os inibidores de PDE5 sildenafil (Viagra ®), vardenafil (Levitra ®) e tadalafil (Cialis ®) são remédios sob prescrição médica tomados oralmente. Eles atuam ao bloquear a ação do PDE5, que causa a degradação do monofosfato de guanosina cíclico (cGMP). O cGMP causa um relaxamento que permite que o sangue preencha o corpo cavernoso do sangue.
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